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SONOVEIN HD
Non-invasive vein treatment
Theraclion’s robotic high-intensity focused ultrasound (HIFU) platform treats selected superficial venous reflux from outside the body. No intravascular catheter or incision is required.
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How HIFU works
Real-time imaging and focused energy
1. Ultrasound visualizes the refluxing vein. 2. Focused energy heats the targeted vein wall. 3. Cooling helps protect surrounding tissues. 4. The vein closes as treatment progresses under robotic positioning.
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Diseases & indications
What conditions can be considered?
PRIMARY APPLICATION: Superficial venous reflux causing symptomatic varicose veins, particularly great saphenous vein (GSV) incompetence. OTHER REPORTED TARGETS: Small saphenous vein (SSV) reflux and incompetent perforating veins. COMPLEX PRESENTATIONS: Selected chronic venous disease and venous leg ulcers associated with incompetent perforators have been described in published reports.
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Patient selection
Clinical assessment matters
Duplex ultrasound is required to establish reflux, map the anatomy and select a suitable target. Disease severity, vein depth, tortuosity, adjacent structures, skin changes and treatment access require physician assessment. Do not present deep vein thrombosis, deep venous obstruction, or all venous ulcers as established SONOVEIN indications.
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Benefits & workflow
From outside the body
Non-invasive transcutaneous energy delivery; integrated ultrasound imaging; robotic guidance; outpatient-oriented workflow; no catheter insertion or general anesthesia in the manufacturer-described treatment pathway. Treatment experience and outcomes vary; consult the current IFU and local approval.
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Clinical evidence I
GSV reflux and pivotal study
2025 VEINRESET U.S. pivotal study announcement: Theraclion reported 96.8% occlusion. This is a manufacturer-reported study result, not a patient-level guarantee or U.S. marketing authorization. Casoni et al., Phlebology (2024): perioperative and 1-year outcomes of HIFU for GSV incompetence. Rodríguez Carvajal et al., Phlebology (2025): preliminary 12-month outcomes for superficial venous insufficiency.
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Clinical evidence II
Perforators and ulcer-related cases
Casoni et al., Phlebology (2025): HIFU treatment of incompetent perforator veins. Obermayer et al., EJVES Vascular Forum (2021): a case report treating an incompetent perforating vein in a patient with an active venous ulcer. Izquierdo Lamoca et al. (2025): HIFU for chronic venous disease using a CHIVA-based strategy. Evidence varies by target and study design.
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Clinical evidence III
Procedure and mechanism studies
Casoni et al. (2024): histopathological analysis of HIFU action on venous walls. Casoni et al. (2024): HIFU-pain study comparing anesthesia protocols. Whiteley et al. (2022): reported one-year results involving truncal and perforator veins; verify publication status and methodology before drawing comparative conclusions.
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Education & videos
Open presentations without QR codes
The SONOVEIN presentations library includes congress sessions on GSV reflux, varicose veins, venous ulcers, and HIFU technology. Tap below to open the manufacturer’s presentation collection. Individual video playback is not embedded because publicly accessible direct video files were not verified.
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Scientific library
Studies organized for physicians
GSV outcomes • SSV feasibility • Perforator incompetence • Venous ulcer case reports • Pain and anesthesia • Histopathology • CHIVA-based treatment. The publications library includes journal papers, case reports, conference material and other sources. Not all carry the same level of evidence.
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Important information
Clinical and regulatory notice
SONOVEIN is CE-marked for coagulation of blood vessels in patients with superficial venous reflux, as described by Theraclion. U.S. status is investigational in the cited materials. This educational catalog is not a substitute for current instructions for use, physician judgment, or Saudi regulatory and promotional review. Source information checked October 2026.